Key result
Increasing ventricular fibrillation duration from 5 to 30 seconds significantly increased the energy required for 90% successful internal defibrillation in dogs (41 vs 27 J; p<0.01).
Why the study?
Does the duration of ventricular fibrillation affect the energy required for successful internal defibrillation in dogs?
Population
15 closed chest dogs with internal electrodes
Comparison
Ventricular fibrillation durations of 5, 15, and… vs Comparison between the different durations
Design
Preclinical
Authors
Loading...
May warrant minimizing VF duration before defibrillation; leaves open translation to human practice.
Does the duration of ventricular fibrillation affect the energy required for successful internal defibrillation in dogs?
Absolute Event Rate: 41% vs 27%
p-value: p=<0.01
Longer durations of ventricular fibrillation increase the energy required for successful internal defibrillation in a canine model.
Echt et al. (1988) studied Ventricular fibrillation (n=15). Ventricular fibrillation duration vs. Shorter duration (5 seconds) was evaluated on 90% successful energy dose (ED90) (p=<0.01). Increasing ventricular fibrillation duration from 5 to 30 seconds significantly increased the energy required for 90% successful internal defibrillation in dogs (41 vs 27 J; p<0.01).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: