Key result
Different defibrillation electrode configurations achieved a 90% success rate at varying energy levels, with Cu spoons requiring 8 J, cross patches 9 J, circular patches 13.5 J, and Ti electrodes 16.5 J.
Why the study?
Does electrode configuration affect the defibrillation threshold and success rate in a canine model of ventricular fibrillation?
Does electrode configuration affect the defibrillation threshold and success rate in a canine model of ventricular fibrillation?
Electrode configuration significantly impacts defibrillation thresholds, suggesting the potential to optimize energy requirements for individual patients.
Electrode configuration affects canine defibrillation thresholds; leaves open translation to human VF optimization.
Intracardiac defibrillation requires the lowest possible defibrillation threshold in order to extend battery life and to increase a safety margin. An optimal choice of size, shape and position of the electrodes with respect to the heart can contribute to this goal. In 11 dogs 349 episodes of ventricular fibrillation were induced and four different defibrillation electrodes used. After ventricular fibrillation was detected a shock with programmable width between 1.5 and 2.4 ms was delivered after 20 seconds. Successful defibrillation was considered if sinus rhythm and adequate aortic pressure were detected. Percentage success rate (%SR) was calculated as: %SR=100/spl times/number of effective shocks/total number of shocks. The threshold/duration curve showed a parabolic behavior with a minimum at 10 ms. Sigmoid curves proved to give a best fit %SR. Ti electrodes showed a 90% SR at 16.5 J, circular patches at 13.5 J, cross patches at 9 J and Cu spoons at 8 J. These results indicate the possibility to optimize electrode configuration and threshold for a individual patient with a limited number of test shocks.
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Aubert et al. (2002) studied Ventricular fibrillation (n=11). Different defibrillation electrodes (Ti, circular patches, cross patches, Cu spoons) was evaluated on Percentage success rate (%SR) of defibrillation. Different defibrillation electrode configurations achieved a 90% success rate at varying energy levels, with Cu spoons requiring 8 J, cross patches 9 J, circular patches 13.5 J, and Ti electrodes 16.5 J.
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