Key result
Acute myocardial ischemia in anesthetized pigs did not influence defibrillation success or the minimum energy required for defibrillation compared to controls.
Why the study?
Does acute myocardial ischemia affect the internal cardiac defibrillation threshold in a pig model?
Population
Halothane-anesthetized pigs
Comparison
Acute myocardial ischemia induced by ligating… vs Controls with loosely tied ligatures placed…
Design
Preclinical
Follow-up
Acute (30 minutes after coronary artery ligation)
Authors
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No adjustment to defibrillation thresholds indicated by acute ischemia; leaves open translation beyond this porcine model.
Does acute myocardial ischemia affect the internal cardiac defibrillation threshold in a pig model?
Acute myocardial ischemia does not appear to alter the internal cardiac defibrillation threshold in a porcine model.
Jones et al. (1986) studied Ventricular fibrillation and acute myocardial ischemia (n=46). Acute myocardial ischemia (LAD ligation) vs. Controls (loosely tied ligatures) was evaluated on Defibrillation success with minimum energy above or below 30 J. Acute myocardial ischemia in anesthetized pigs did not influence defibrillation success or the minimum energy required for defibrillation compared to controls.
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