Why the study?
What is the incidence, electrophysiological characteristics, and ablation success rate of left atrial tachycardia following circumferential pulmonary vein ablation for atrial fibrillation?
What is the incidence, electrophysiological characteristics, and ablation success rate of left atrial tachycardia following circumferential pulmonary vein ablation for atrial fibrillation?
Left atrial re-entrant tachycardia is a frequent complication (31%) following circumferential pulmonary vein ablation for AF, and its mapping and ablation can be challenging due to unstable variants and small-loop re-entries.
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LA tachycardia frequently complicates CPVA; leaves open optimal mapping for unstable circuits in prospective studies.
AIMS: To investigate the incidence, electrophysiological properties, and ablation results for left atrial (LA) tachycardia as a sequel to the circumferential pulmonary vein ablation (CPVA) for atrial fibrillation (AF). METHODS AND RESULTS: Sixty-seven patients with AF underwent CPVA. Sustained LA tachycardia developed in 21/67 (31%) patients and in 16/21 symptomatic patients 55 LA tachycardias (3.4+/-2.4 per patient) were mapped: 18 (33%) tachycardias were related to macro-re-entry around the mitral valve (7) or pulmonary vein(s) (11). In 20 tachycardias (36%), a 'small-loop' LA re-entrant tachycardia (LART) was identified; gaps in prior ablation lines (7 LART) or an area of extremely slow conduction adjacent to the CPVA lesions (13 LART) were crucial for these re-entries. Seventeen tachycardias (31%) were too unstable for complete mapping. Ablation was a primary success in 34 of 38 (89%) mapped LART, but in eight of 21 procedures, cardioversion was necessary to achieve sinus rhythm. CONCLUSION: LART develops in a high percentage of patients after CPVA. Small-loop re-entry, which is difficult to map, may arise and patients suffer from several and/or unstable variants of LART. Thus, mapping and ablation of these LART is challenging and the overall success is yet not satisfactory.
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Deisenhofer et al. (2006) studied this question.
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