What question did this study set out to answer?

To describe the coronary sinus as a potential single source of paroxysmal atrial fibrillation.

July 30, 2007Pacing and Clinical Electrophysiology

The Coronary Sinus as a Focal Source of Paroxysmal Atrial Fibrillation: More Evidence for the ‘Fifth Pulmonary Vein’?

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Why the study?

Does radiofrequency ablation of the proximal coronary sinus eliminate paroxysmal atrial fibrillation originating from this site?

Key Points

To describe the coronary sinus as a potential single source of paroxysmal atrial fibrillation.
Reported a case of a patient with paroxysmal AF and arrhythmogenic focus in the proximal coronary sinus.
Characterized the spike potential preceding AF using electrograms during both AF and sinus rhythm.
Performed radiofrequency ablation at the identified site within the coronary sinus.
Achieved elimination of the spike potential after ablation.
Resulted in disappearance of atrial fibrillation and confirmed it was noninducible post-procedure.

Structured PICO

Does radiofrequency ablation of the proximal coronary sinus eliminate paroxysmal atrial fibrillation originating from this site?

Population

1 patient with paroxysmal atrial fibrillation

Intervention

Radiofrequency ablation at the proximal coronary sinus

Outcome

Elimination of the spike potential, disappearance and noninducibility of atrial fibrillation

The coronary sinus can act as a single focal source initiating and driving paroxysmal atrial fibrillation, which can be successfully treated with targeted radiofrequency ablation.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

May support proximal coronary sinus as focal AF trigger in select cases; hypothesis-generating and requires prospective validation.

Cite This Study

Rostock et al. (2007) studied this question.

synapsesocial.com/papers/6a217e1d136b3fb47d8b6950 https://doi.org/10.1111/j.1540-8159.2007.00805.x

Topics

Atrial fibrillation Persistent AF management AF ablation outcomes Anticoagulation in AF

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The Coronary Sinus as a Focal Source of Paroxysmal Atrial Fibrillation: More Evidence for the ‘Fifth Pulmonary Vein’?

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Topics

The Coronary Sinus as a Focal Source of Paroxysmal Atrial Fibrillation: More Evidence for the ‘Fifth Pulmonary Vein’?

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider