Key result
Among Chinese women, each additional pregnancy was associated with a higher risk of circulatory disease (HR 1.03), and a history of miscarriage, induced abortion, and stillbirth were also associated with increased cardiovascular risk.
Why the study?
Does pregnancy and pregnancy loss increase the risk of cardiovascular disease in Chinese women?
Population
289,573 Chinese women aged 30-79 years without prior cardiovascular disease at baseline, recruited from ten…
Comparison
Pregnancy and pregnancy loss vs Women with fewer pregnancies or no history of…
Design
Cohort
Follow-up
median 7.1 years
Authors
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May inform CVD risk assessment in Chinese women but should not change practice; extends prior associations to this population.
Cohort (n=289,573)
Yes
Does pregnancy and pregnancy loss increase the risk of cardiovascular disease in Chinese women?
Hazard Ratio: 1.03 (95% CI 1.02–1.04)
Among Chinese women, an increasing number of pregnancies and a history of pregnancy loss (miscarriage, induced abortion, stillbirth) are associated with a higher risk of incident cardiovascular disease.
Peters et al. (2017) conducted a cohort in Cardiovascular disease (n=289,573). Pregnancy and pregnancy loss vs. Fewer pregnancies or no history of pregnancy loss was evaluated on Incident circulatory disease per additional pregnancy (HR 1.03, 95% CI 1.02-1.04). Among Chinese women, each additional pregnancy was associated with a higher risk of circulatory disease (HR 1.03), and a history of miscarriage, induced abortion, and stillbirth were also associated with increased cardiovascular risk.
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