Why the study?
Does advancing age diminish the capacity to develop myocardial hypertrophy in response to acute pressure overload in rats?
Does advancing age diminish the capacity to develop myocardial hypertrophy in response to acute pressure overload in rats?
Advancing age is associated with a diminished capacity to develop myocardial hypertrophy in response to acute pressure overload in a rat model.
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Advancing age blunts hypertrophic response to pressure overload in rats; leaves open relevance to human cardiac remodeling with aging.
Isoyama et al. (1987) studied this question.
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