Key result
Hypertension and AFib strongly associate with elderly stroke incidence, though their impact shifts with age.
Why the study?
Stroke is a leading cause of disability and mortality in people over 65 years of age, making understanding the management of modifiable risk factors and recognizing non-modifiable risk factors crucial for stroke prevention.
Understanding the age-specific impact of modifiable and non-modifiable cardiovascular risk factors is crucial for effective stroke prevention in the growing elderly population.
Supports age-specific hypertension and AF focus in elderly stroke prevention; leaves open precise risk weighting for prospective studies.
By the year 2050 there will be around 426 million people over 80 years of age. As lifespan is extended, cardiovascular risk factors are becoming one of many challenges. Cardiovascular diseases are the leading cause of death at the age over 65. Stroke is also one of the leading causes of disability and mortality. It is estimated that 75% of strokes occur in people over 65 years of age. Understanding how to manage modifiable risk factors for stroke and recognizing the influence of non-modifiable risk factors is crucial. Age is a leading factor in a non-modifiable group of stroke risk factors. Gender is also highlighted due to socioeconomic and biological differences between men and women. Modifiable risk factors for stroke are diabetes mellitus (DM), obesity, psychosocial factors, dyslipidemia, smoking, physical inactivity, diet, alcohol intake, high blood pressure and other cardiovascular diseases like atrial fibrillation (AF), with hypertension being one of the most important risk factors in the group of elderly patients. Knowing more about the associations of these risk factors with stroke in different age groups can help with better management and stroke prevention.
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Stojanovski et al. (2024) conducted a review in Stroke. Cardiovascular risk factors was evaluated. Modifiable cardiovascular risk factors, particularly hypertension and atrial fibrillation, play a crucial role in the incidence of stroke among the elderly, though their relative impact may change with advancing age.
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