Key result
A commercial direct fluorescent-antibody assay for human metapneumovirus demonstrated 95.2% sensitivity, 100% specificity, and 98.9% accuracy compared to reverse transcriptase PCR.
Why the study?
Does a commercial direct fluorescent-antibody assay kit accurately detect human metapneumovirus in respiratory specimens compared to reverse transcriptase PCR?
Does a commercial direct fluorescent-antibody assay kit accurately detect human metapneumovirus in respiratory specimens compared to reverse transcriptase PCR?
A commercial direct fluorescent-antibody assay kit provides highly accurate detection of human metapneumovirus in respiratory specimens.
The performance of a commercially manufactured direct fluorescent-antibody assay kit for human metapneumovirus was compared to that of reverse transcriptase PCR, the current "gold standard." The kit demonstrated a sensitivity of 95.2%, a specificity of 100%, and an accuracy of 98.9%.
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Vinh et al. (2008) studied this question. A commercial direct fluorescent-antibody assay for human metapneumovirus demonstrated 95.2% sensitivity, 100% specificity, and 98.9% accuracy compared to reverse transcriptase PCR.
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