Key result
Compensatory cardiac hypertrophy induces phenotypic membrane changes and ionic current imbalances that prolong action potentials and calcium transients, favoring arrhythmias.
Cellular adaptational modifications in cardiac hypertrophy, including altered ion currents and calcium handling, contribute to arrhythmogenesis alongside ventricular fibrosis.
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May increase arrhythmia risk in hypertrophy; leaves open targeted interventions pending clinical validation.
Bernard Swynghedauw (1997) conducted a review in Compensatory cardiac hypertrophy. Compensatory cardiac hypertrophy was evaluated. Compensatory cardiac hypertrophy induces phenotypic membrane changes and ionic current imbalances that prolong action potentials and calcium transients, favoring arrhythmias.
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