Population
Rabbits anaesthetized with pentobarbitone sodium (some paralysed and artificially ventilated)
Design
Preclinical
Authors
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Vagal modulation of proximal airways should not yet inform clinical practice; leaves open selective effects on human lung resistance versus compliance.
In rabbits, vagal efferent activity primarily affects larger resistance air passages with little action on distal compliance-influencing airways.
Karczewski et al. (1969) studied this question.
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