Key result
Exaggerated blood pressure response to exercise is a marker of masked hypertension, poor blood pressure control, subclinical target organ damage, and an increased risk of adverse cardiovascular outcomes.
Why the study?
Exaggerated blood pressure response to exercise is associated with adverse cardiovascular outcomes and masked hypertension, prompting an up-to-date review of its clinical importance.
Does an exaggerated blood pressure response to exercise predict future hypertension and cardiovascular events in normotensive and hypertensive individuals?
Does an exaggerated blood pressure response to exercise predict future hypertension and cardiovascular events in normotensive and hypertensive individuals?
Exaggerated blood pressure response to exercise is an important clinical marker that identifies individuals at increased risk for masked hypertension, target organ damage, and future cardiovascular events.
May prompt enhanced risk stratification during exercise testing; leaves open prospective validation and therapeutic implications.
The hypertensive response to exercise testing, defined as exaggerated blood pressure response (EBPR), has been documented to be independently associated with unhealthy conditions, carrying an increased risk of future hypertension, cardiovascular (CV) morbidity and mortality. In treated hypertensives, EBPR is a marker of uncontrolled hypertension, a condition previously undetected by office blood pressure (BP) measurements at rest; EBPR may also detect masked hypertension, a phenotype characterized by normal BP values in the medical environment but elevated home or ambulatory BP monitoring (ABPM). The aim of the present review is to provide a comprehensive and up-dated information on the clinical importance of EBPR targeting the following issues: (I) definition and prevalence; (II) underlying mechanisms; (III) clinical correlates and association with subclinical organ damage; (IV) predictive value; (V) clinical decision making.
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Cuspidi et al. (2023) conducted a review in Exaggerated blood pressure response to exercise. Exaggerated blood pressure response to exercise vs. Normal blood pressure response to exercise was evaluated. Exaggerated blood pressure response to exercise is a marker of masked hypertension, poor blood pressure control, subclinical target organ damage, and an increased risk of adverse cardiovascular outcomes.
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