Key result
Convergent atrial fibrillation ablation significantly reduced the area of the terminal negative deflection of the P wave in lead V1 from 0.38 mm2 to 0.13 mm2 (p=0.03).
Why the study?
Does convergent atrial fibrillation ablation change the morphology of the surface P wave in patients with atrial fibrillation?
Observational (n=29)
Does convergent atrial fibrillation ablation change the morphology of the surface P wave in patients with atrial fibrillation?
Absolute Event Rate: 0.13% vs 0.38%
p-value: p=0.03
Convergent atrial fibrillation ablation significantly alters P wave morphology, particularly reducing the terminal negative deflection in V1, which is important for diagnosing subsequent atrial arrhythmias.
May aid post-ablation arrhythmia diagnosis; observational data leaves open prospective validation.
Convergent atrial fibrillation ablation involves extensive epicardial as well as endocardial ablation of the left atrium. We examined whether it changes the morphology of the surface P wave. We reviewed electrocardiograms of 29 patients who underwent convergent ablation for atrial fibrillation. In leads V1, II and III, we measured P wave duration, area and amplitude before ablation, and at 1, 3 and 6 months from ablation. After ablation, there were no significant changes in P wave amplitude, area, or duration in leads II and III. There was a significant reduction in the area of the terminal negative deflection of the P wave in V1 from 0.38 mm(2) to 0.13 mm(2) (p = 0.03). There is also an acute increase in the amplitude and duration of the positive component of the P wave in V1 followed by a reduction in both by 6 months. Before ablation, 62.5% of the patients had biphasic P waves in V1. In 6 months, only 39.2% of them had biphasic P waves. Hybrid ablation causes a reduction of the terminal negative deflection of the P wave in V1 as well as temporal changes in the duration and amplitude of the positive component of the P wave in V1. This likely reflects the reduced electrical contribution of the posterior left atrium after ablation as well as anatomical and autonomic remodeling. Recognition of this altered sinus P wave morphology is useful in the diagnosis of atrial arrhythmias in this patient population.
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Shrestha et al. (2016) conducted an observational in Atrial fibrillation (n=29). Convergent atrial fibrillation ablation vs. Pre-ablation baseline was evaluated on Area of the terminal negative deflection of the P wave in lead V1 (mm2) (p=0.03). Convergent atrial fibrillation ablation significantly reduced the area of the terminal negative deflection of the P wave in lead V1 from 0.38 mm2 to 0.13 mm2 (p=0.03).
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