Key result
Premature closure of the mitral valve in a patient with aortic regurgitation and first-degree heart block produced an audible presystolic first heart sound, supporting its valvular origin.
Case Report (n=1)
The observation of a presystolic first heart sound associated with premature mitral valve closure provides further support for the valvular origin of the first heart sound.
Supports valvular S1 origin in AR with AV block; extends observations but leaves open prospective validation.
We report a patient who developed aortic regurgitation and first degree atrioventricular block caused by infective endocarditis complicating aortic valve stenosis. There was premature closure of the mitral valve and, in the absence of an Austin Flint murmur, a simultaneous high frequency sound was audible which we regard as a presystolic first heart sound. That such a sound may be associated with valve closure, even though this precedes electrical and mechanical ventricular systole, provides further support for the valvular origin of the first heart sound.
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Traill et al. (1982) conducted a case report in Aortic regurgitation and first degree atrioventricular block caused by infective endocarditis complicating aortic valve stenosis (n=1). Premature closure of the mitral valve was evaluated on Presystolic first heart sound. Premature closure of the mitral valve in a patient with aortic regurgitation and first-degree heart block produced an audible presystolic first heart sound, supporting its valvular origin.
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