Key result
Type 2 diabetes mellitus was associated with a significantly higher prevalence of multivessel coronary artery disease compared to nondiabetics (73% vs 50%; P=0.003).
Why the study?
The absolute risk of CAD death is two to five times higher in patients with diabetes, prompting investigation into their angiographic severity and extent of CAD compared with nondiabetic patients.
Does Type 2 diabetes mellitus increase the angiographic severity and extent of coronary artery disease compared to nondiabetic patients?
Cross-Sectional (n=340)
Does Type 2 diabetes mellitus increase the angiographic severity and extent of coronary artery disease compared to nondiabetic patients?
Answers are grounded in this paper and cite their sources.
Type 2 diabetes is associated with a significantly higher prevalence of multivessel and diffuse coronary artery disease compared to nondiabetic patients.
Background/Aim: The absolute risk of death due to coronary artery disease (CAD) is two to five times higher in patients with diabetes than in those without diabetes regardless of the cholesterol concentration, and females with diabetes have the worst prognosis. The aim of the current study was to investigate the angiographic severity and extent of CAD in patients with Type 2 diabetes mellitus, compared with nondiabetic patients. Patients and Methods: A hospital-based retrospective cross-sectional study was performed on 340 patients who were diagnosed with CAD. The two groups were matched for age, gender, and other major risk factors. Data collected include demographic data, distribution, and extent of coronary artery involvement. Results: Three hundred and forty patients were included in the study, 175 of them (51.4%) were diabetics, and 165 (48.5%) were nondiabetics, comparing coronary angiographic results of both groups: One hundred and twenty-six patients (73%) of the diabetic patients have multivessel diseased ( P = 0.003), 49 patients (27%) have a single-vessel diseased and none of them have a normal coronaries (0%). While for the nondiabetic patients 82 (50%) of them have a multivessel diseased, 63 patients (38%) have a single-vessel diseased, and 20 patients (12%) have normal coronaries. Conclusion: Multivessel disease with diffuse lesion is more prevalent among diabetic Libyan patients compared with nondiabetics. The affected vessels in diabetic patients are diffusely diseased more than nondiabetic.
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Bettamer et al. (2021) conducted a cross-sectional in Coronary artery disease (CAD) (n=340). Type 2 diabetes mellitus vs. Nondiabetic was evaluated on Multivessel disease (p=0.003). Type 2 diabetes mellitus was associated with a significantly higher prevalence of multivessel coronary artery disease compared to nondiabetics (73% vs 50%; P=0.003).
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