A study of the value of small doses of platelets given prophylactically in thrombocytopenic patients was carried out. Transfusions of two dose levels of platelets were compared: 0.03 units/1b (low dose) and 0.06 units/lb of body weight (high dose). The incidence of bleeding in nontransfused patients seen here prior to this study was also determined. The difference in incidences of bleeding among patients transfused with low or high dose was not significant. The differences between the transfused and nontransfused patients were highly significant.
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Roy et al. (1973) studied this question.
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