Eight biomarkers on a novel strip for early diagnosis of acute myocardial infarction

Figures

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  Scheme 1. Schematic illustration of the eight biomarker strip for AMI.

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  Fig. 1. The SEM micrographs of the fluorescent latex microspheres at different magnifications. (a) ×10 000 and (b) ×50 000.

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  Fig. 2. (a–g) The calibration curves of TC, TG, HDL-C, UA, CK-MB, cTnI and Myo. The error bars indicate the standard deviations calculated from three tests.

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  Fig. 3. The selectivity of the prepared strips for cTnI detection. 50 ng mL−1 for cTnI and 500 ng mL−1, 500 ng mL−1, 50 mmol L−1, 50 mmol L−1, 50 mmol L−1, and 50 mmol L−1 for CK-MB, Myo, TC, TG, UA, and HDL-C, respectively, tested in three parallel measurements.

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  Fig. 4. Passing–Bablok regression lines between the results obtained from clinical methods and the strip for TC, TG, HDL-C, UA, Myo, CK-MB and cTnI (a–g) detection in real serum samples (in the figures, the solid lines represent the linear regression line, with the dashed lines showing the range of 95% CI).