Key result
Congestive heart failure was associated with significantly lower left atrial mechanical function, including peak LA strain, strain rate, and tissue velocity, compared to hypertension and normal controls.
Why the study?
Is left atrial mechanical function decreased in patients with congestive heart failure compared to hypertensive and normal individuals when assessed by speckle tracking and tissue Doppler echocardiography?
Cross-Sectional (n=126)
Is left atrial mechanical function decreased in patients with congestive heart failure compared to hypertensive and normal individuals when assessed by speckle tracking and tissue Doppler echocardiography?
Speckle tracking and tissue Doppler echocardiography demonstrate that left atrial mechanical function is significantly decreased in patients with congestive heart failure.
Supports speckle tracking for LA assessment in HF; hypothesis-generating pending prospective validation.
Mechanical dysfunction of left atrium (LA) could be documented by tissue Doppler and speckle tracking echocardiography in patients with congestive heart failure (CHF). This study included 28 CHF, 46 untreated hypertension (HT), and 52 normal (NM) individuals with normal sinus rhythm. LA volumes and emptying fraction (LAEF) were measured by biplane area-length method. Peak LA strain (LAS) and strain rate (LASR) measured from speckle tracking echocardiography were identified as the peak negative deflection after P-wave. Tissue velocity (LATV) and tissue Doppler-derived strain (LATS) of LA were also used as indices of LA mechanical function. LAEF, LAS, LASR, LATV, and LATS were significantly lower in CHF than in HT and NM. After multivariate analysis controlling for age and sex, LAS, LASR, and LATV were still significantly lower in CHF. LASR was significantly correlated with LAEF. In conclusion, LA mechanical function was decreased in patients with CHF.
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Tsai et al. (2012) conducted a cross-sectional in Congestive Heart Failure (n=126). Congestive heart failure vs. Untreated hypertension and normal individuals was evaluated on Left atrial mechanical function (LAEF, LAS, LASR, LATV, LATS). Congestive heart failure was associated with significantly lower left atrial mechanical function, including peak LA strain, strain rate, and tissue velocity, compared to hypertension and normal controls.
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