Key result
Laparoscopic sleeve gastrectomy improved global longitudinal strain from -16.06% at baseline to -17.48% at 6 months in obese patients without known heart disease (P < .001).
Why the study?
The study aimed to investigate early and mid-term left ventricular function by speckle tracking echocardiography in obese patients without known heart disease undergoing laparoscopic sleeve gastrectomy.
Does laparoscopic sleeve gastrectomy improve left ventricular function assessed by speckle tracking echocardiography in obese patients without known heart disease?
Observational (n=37)
Does laparoscopic sleeve gastrectomy improve left ventricular function assessed by speckle tracking echocardiography in obese patients without known heart disease?
Laparoscopic sleeve gastrectomy in obese patients without known heart disease is associated with improved left ventricular global longitudinal strain at 6 months.
Sleeve gastrectomy was associated with improved GLS in obese patients without known heart disease; extends observational evidence for subclinical LV benefits but leaves open need for RCTs.
AIM: This study aimed to investigate left ventricular functions of obese patients with no known heart disease who underwent laparoscopic sleeve gastrectomy by speckle tracking echocardiography in their early and medium-term postoperative follow-up. PATIENTS AND METHOD: Thirty-seven obese patients (10 M, 27 F) without coronary artery disease or heart failure who had undergone LSG were included in the study. Apical four-, three-, and two-chamber images were analyzed longitudinally by conventional methods and speckle tracking echocardiography (STE) for left ventricle functions preoperatively, at the postoperative Month 1 and at the postoperative Month 6 (QLAB 6.0), using current software. RESULTS: No difference was found between standard echocardiography and Doppler parameters in terms of the 1-month versus 6-month follow-up values compared to baseline. Left ventricular STE longitudinal measurements demonstrated significantly higher longitudinal strain and strain velocity parameters in the follow-up values at Month 6 compared to the values at Month 1 and at baseline. Global longitudinal strain (GLS) was -17.48 ± 1.09% in 6-month follow-up, -16.16 ± 1.26% in 1-month follow-up, and -16.06 ± 1.25% at baseline (P < .001). A significant correlation was found between delta GLS, which represents patients' GLS change in 6 months, and delta weight, which represents patients' body weight change in 6 months. CONCLUSION: Obese patients who had undergone LSG were observed to have improved left ventricular function in the mid-term.
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İnci et al. (2019) conducted an observational in Obesity (n=37). Laparoscopic sleeve gastrectomy vs. Baseline (preoperative) was evaluated on Global longitudinal strain (GLS) (p=< .001). Laparoscopic sleeve gastrectomy improved global longitudinal strain from -16.06% at baseline to -17.48% at 6 months in obese patients without known heart disease (P < .001).
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