Key result
Sleeve gastrectomy significantly improved left ventricular systolic function and contributed to reverse LV remodeling at 6 months in 53 obese patients, with similar benefits in men and women.
Why the study?
Does sleeve gastrectomy improve left ventricular systolic function and reverse remodeling in obese men and women?
Cohort (n=53)
Does sleeve gastrectomy improve left ventricular systolic function and reverse remodeling in obese men and women?
Sleeve gastrectomy leads to significant weight loss and reverse left ventricular remodeling with improved systolic function at 6 months, with similar benefits observed in both men and women.
Answers are grounded in this paper and cite their sources.
May support cardiac benefits of sleeve gastrectomy in obesity; hypothesis-generating and requires RCTs to confirm causality.
PURPOSE: To evaluate and compare the effects of weight lost after sleeve gastrectomy on left ventricular (LV) systolic function using both two-dimensional speckle tracking (2D-STE) and three-dimensional echocardiography (3DE) in men versus women. METHODS: In 53 obese patients referred for sleeve gastrectomy, 2D-STE and 3DE were performed prior to and 6 months after surgery. RESULTS: The study included 53 obese patients (62.3% female; mean age 36.8 ± 10.7 years). Six months after surgery, all patients demonstrated a significant decrease in body mass index, body weight, blood pressure, heart rate, LV end-diastolic dimension, myocardial wall thickness, LV mass, LV mass index, LV mass/height(2.7) , LV end-diastolic volume, LV end-systolic volume, and stroke volume as well as an increase in SV index and ejection fraction. There was no significant difference in measured variables between men and women at baseline or postsurgery, except for baseline LV end-diastolic dimension, and baseline and after surgery LV mass, LV mass index, and LV mass/height(2.7) , which were all significantly higher in men. CONCLUSIONS: Sleeve gastrectomy improves LV systolic function and contributes to reverse LV remodeling in both genders.
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Öz et al. (2016) conducted a cohort in Obesity (n=53). Sleeve gastrectomy vs. Baseline (pre-surgery) and between genders was evaluated on Left ventricular (LV) systolic function and reverse LV remodeling. Sleeve gastrectomy significantly improved left ventricular systolic function and contributed to reverse LV remodeling at 6 months in 53 obese patients, with similar benefits in men and women.
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