Why the study?
Does 12 months of dual antiplatelet therapy prevent stent thrombosis, myocardial infarction, and death in patients with coronary artery stents?
Does 12 months of dual antiplatelet therapy prevent stent thrombosis, myocardial infarction, and death in patients with coronary artery stents?
This science advisory emphasizes the critical need for 12 months of uninterrupted dual antiplatelet therapy following drug-eluting stent placement to prevent catastrophic ischemic events.
Requires 12-month DAPT adherence post-DES with 1-year elective surgery delay; reinforces consensus to minimize stent thrombosis and MI.
Dual antiplatelet therapy with aspirin and a thienopyridine has been shown to reduce cardiac events after coronary stenting. However, many patients and healthcare providers prematurely discontinue dual antiplatelet therapy, which greatly increases the risk of stent thrombosis, myocardial infarction, and death. This advisory stresses the importance of 12 months of dual antiplatelet therapy after placement of a drug‐eluting stent and educating the patient and healthcare providers about hazards of premature discontinuation. It also recommends postponing elective surgery for 1 year, and if surgery cannot be deferred, considering the continuation of aspirin during the perioperative period in high‐risk patients with drug‐eluting stents.
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Grines et al. (2007) studied this question.
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