Key result
Noninvasive stereotactic ablative radiotherapy guided by computational 12-lead ECG mapping successfully eliminated recurrent ventricular tachycardia over an 18-month follow-up period.
Why the study?
Traditional catheter ablation is challenging in patients presenting with refractory VT and aortic and mitral mechanical prosthetic valves.
Does noninvasive 12-lead ECG mapping-guided stereotactic ablative radiotherapy eliminate VT in a patient with refractory VT and mechanical aortic and mitral valves?
Case Report (n=1)
No
Does noninvasive 12-lead ECG mapping-guided stereotactic ablative radiotherapy eliminate VT in a patient with refractory VT and mechanical aortic and mitral valves?
Noninvasive 12-lead ECG mapping-guided stereotactic ablative radiotherapy successfully eliminated refractory VT over 1.5 years in a patient with inaccessible ventricular substrate due to dual mechanical valves.
Answers are grounded in this paper and cite their sources.
May offer noninvasive option for refractory VT with inaccessible substrate due to mechanical valves; hypothesis-generating case report requiring prospective validation.
In patients presenting with refractory ventricular tachycardia (VT) and aortic and mitral mechanical prosthetic valves, traditional catheter ablation is challenging. We describe a case in which a novel noninvasive computational electrocardiogram mapping algorithm localized VT sources originating from substrate near the mechanical valves, in which stereotactic ablative radiotherapy eliminated VT in 1.5-year follow-up. (Level of Difficulty: Advanced.)
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Keyt et al. (2023) conducted a case report in Refractory ventricular tachycardia (n=1). Noninvasive stereotactic ablative radiotherapy (SAbR) guided by computational 12-lead ECG mapping was evaluated on Recurrence of ventricular tachycardia. Noninvasive stereotactic ablative radiotherapy guided by computational 12-lead ECG mapping successfully eliminated recurrent ventricular tachycardia over an 18-month follow-up period.
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