Key result
Single-catheter primary PCI for STEMI was associated with shorter door-to-balloon time (68 vs. 74 min; p=0.02) and lower radiation exposure (1,664 vs. 2008 mGy; p<0.0001).
Why the study?
Reducing total ischemic time is important in emergency treatment of STEMI, but no established methods existed in primary PCI to shorten ischemic time via radial access.
Does the single-catheter percutaneous coronary intervention (SC-PCI) method reduce door-to-balloon time and radiation exposure dose in patients with STEMI undergoing primary PCI?
Cohort (n=1,275)
Yes
Does the single-catheter percutaneous coronary intervention (SC-PCI) method reduce door-to-balloon time and radiation exposure dose in patients with STEMI undergoing primary PCI?
Absolute Event Rate: 68% vs 74%
p-value: p=0.02
The single-catheter PCI method significantly reduces door-to-balloon time and radiation exposure compared to conventional PCI in patients with STEMI.
Supports single-catheter PCI evaluation in STEMI; leaves open need for randomized confirmation before practice change.
OBJECTIVES: The objectives of this study is to confirm reduction of door-to-balloon (D2B) time with single-catheter percutaneous coronary intervention (SC-PCI) method. BACKGROUND: Reduction of total ischemic time is important in the emergency treatment of ST-elevation myocardial infarction (STEMI). There have been no established methods in primary percutaneous coronary intervention (PCI) to shorten ischemic time via radial access. Ikari left curve was reported as a universal guiding catheter for left and right coronary arteries. Several procedure steps can be skipped by SC-PCI method as the advantage of a universal catheter. METHODS: This study is a retrospective analysis of a total of 1,275 consecutive STEMI cases treated with primary PCI in 14 hospitals. Patients were divided into two groups, SC-PCI method (n = 298) and conventional PCI method (n = 977). Primary endpoints were door-to-balloon (D2B) time and radiation exposure dose. RESULTS: The mean age was 68 ± 13 years old. Radial access was used in 85% of participants. PCI success was achieved in 99.5% of participants and the SC-PCI method was successfully performed in 92.6%. The D2B time was shorter (68 ± 46 vs. 74 ± 50 min, respectively; p = .02), and the radiation exposure dose was lower (1,664 ± 970 vs. 2008 ± 1,605 mGy, respectively; p < .0001) in the SC-PCI group than in the conventional group. CONCLUSION: Primary PCI with SC-PCI method for patients with STEMI demonstrated shorter D2B time and lower radiation exposure dose.
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Lee et al. (2021) conducted a cohort in ST-elevation myocardial infarction (STEMI) (n=1,275). Single-catheter percutaneous coronary intervention (SC-PCI) method vs. Conventional PCI method was evaluated on Door-to-balloon (D2B) time and radiation exposure dose (p=0.02). Single-catheter primary PCI for STEMI was associated with shorter door-to-balloon time (68 vs. 74 min; p=0.02) and lower radiation exposure (1,664 vs. 2008 mGy; p<0.0001).
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