Key result
Long-term use of antihypertensive therapy has raised concerns regarding cancer risk, but current evidence remains inconclusive and requires further investigation.
Why the study?
Recent evidence focused attention on the cancer risk potentially associated with long-term antihypertensive therapy, prompting a summary of available evidence surrounding three recent events.
Does long-term use of antihypertensive therapy increase cancer risk in patients with hypertension?
Does long-term use of antihypertensive therapy increase cancer risk in patients with hypertension?
This review highlights the ongoing uncertainty and need for further studies regarding the potential cancer risk associated with long-term antihypertensive therapy.
Answers are grounded in this paper and cite their sources.
Current evidence does not support altering antihypertensive regimens over cancer concerns; leaves open the need for prospective trials.
The recent decrease in mortality related to cardiovascular diseases has largely been due to the more effective treatment of cardiovascular risk factors and secondary prevention therapies. More people than ever are now on long-term medications. Hypertension, which is one of the most common cardiovascular risk factors, requires life-long treatment. Recent evidence has focused attention on the risk of cancer that may be associated with the long-term use of antihypertensive therapy. This article summarises available evidence surrounding three recent events in this setting. Even though this is a crucial patient safety issue, there are no conclusive answers at this time and further studies are required.
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Battistoni et al. (2020) conducted a review in Hypertension. Antihypertensive therapy was evaluated on Cancer risk. Long-term use of antihypertensive therapy has raised concerns regarding cancer risk, but current evidence remains inconclusive and requires further investigation.
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