Key result
A finite element computational model established a direct relation between a normal positive T-wave and the non-uniform distribution of refractoriness in the human heart.
Population
Computational model of the human heart calibrated using clinically measured action potential durations
Design
Other
Authors
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Does not inform clinical T-wave assessment; leaves open prospective validation of refractoriness models.
A calibrated finite element model of the human heart successfully links microscopic action potential durations to macroscopic repolarisation sequences, providing a framework for exploring cardiac excitation.
Hurtado et al. (2012) studied Cardiac electrophysiology (repolarisation and T-wave polarity). Finite element computational modeling was evaluated on Regional and temporal variations in depolarisation and repolarisation. A finite element computational model established a direct relation between a normal positive T-wave and the non-uniform distribution of refractoriness in the human heart.
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