Key result
Digoxin and pindolol were effective in controlling ventricular response in elderly patients with chronic atrial fibrillation, with digoxin being the best tolerated.
Why the study?
Does oral administration of pindolol, verapamil, digoxin, or digoxin + pindolol improve control of ventricular response in elderly patients with chronic atrial fibrillation?
RCT (n=8)
Does oral administration of pindolol, verapamil, digoxin, or digoxin + pindolol improve control of ventricular response in elderly patients with chronic atrial fibrillation?
In elderly patients with chronic atrial fibrillation, digoxin is well tolerated for rate control, and the addition of a beta-blocker (pindolol) effectively reduces maximum ventricular rate.
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Supports digoxin as well-tolerated rate-control option in elderly chronic AF; hypothesis-generating case report requiring randomized confirmation.
Wang et al. (1980) conducted an RCT in age-related chronic atrial fibrillation (n=8). Pindolol, verapamil, digoxin, and digoxin + pindolol vs. Placebo was evaluated on Control of ventricular response. Digoxin and pindolol were effective in controlling ventricular response in elderly patients with chronic atrial fibrillation, with digoxin being the best tolerated.
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