Key result
Acute psychological stress affects hemoconcentration and hemostasis, and traditional methods of adjusting for stress-hemoconcentration effects may be inappropriate.
Why the study?
Does acute psychological stress affect hemoconcentration and hemostasis independently or interactively?
This review highlights that stress-induced changes in hemostasis should be evaluated in conjunction with hemoconcentration, as traditional adjustment methods may be inappropriate.
Stress may confound hemostasis marker interpretation; leaves open optimal hemoconcentration adjustment methods for future studies.
BACKGROUND: Acute psychological stress can produce significant hemoconcentration as well as prothrombotic changes in blood, both of which may have potentially harmful effects on the cardiovascular system. It is unclear whether these effects are independent or have influence on each other. PURPOSE: This review discusses research investigating the effects of acute psychological stress on hemoconcentration and hemostasis and explores future directions for psychohematology research. Physiology, associations with cardiovascular disease, and relationships between acute psychological stress are discussed independently for hemoconcentration and hemostasis, followed by an examination of the effects of stress-hemoconcentration on hemostasis. CONCLUSIONS: Traditional methods of adjusting for stress-hemoconcentration effects (e.g., calculated plasma volume or hematocrit level corrections) may not be appropriate when examining stress-induced changes in hemostasis. The effects of acute stress on hemostasis should be examined in conjunction with hemoconcentration.
No takes yet. Share an insight, caveat, or question.
Austin et al. (2011) conducted a review in Acute psychological stress. Acute psychological stress was evaluated on Hemoconcentration and hemostasis. Acute psychological stress affects hemoconcentration and hemostasis, and traditional methods of adjusting for stress-hemoconcentration effects may be inappropriate.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: