Physiology of the Juxtaglomerular Cells

Article1 February 1960PHYSIOLOGY OF THE JUXTAGLOMERULAR CELLSLOUIS TOBIAN, M.D.LOUIS TOBIAN, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-52-2-395 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe juxtaglomerular cells in the kidney were first described by Ruyter1in 1925, and were studied extensively by Goormaghtigh2twenty years ago. They have remained in relative medical obscurity, however, mainly because they cannot readily be seen in the usual H and E histologic preparations. The cells have all the appearances of secretory cells, with secretory granules in their cytoplasm. They are found in all mammals, including man. They actually lie in the wall of the afferent arteriole, particularly in the part quite near the glomerulus (figure 1). These cells are always in an intimate relationship with a group of...Bibliography1. 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Author, Article, and Disclosure InformationAffiliations: Minneapolis, Minnesota*Received for publication October 1, 1959.Presented at the Fortieth Annual Session of The American College of Physicians, Chicago, Illinois, April 20, 1959.From the Department of Medicine, University of Minnesota School of Medicine, and the University of Minnesota Hospitals, Minneapolis.†This work has been supported by a grant from the American Heart Association and by grant No. H-2008 of the National Heart Institute, U. S. Public Health Service.Requests for reprints should be addressed to Louis Tobian, M.D., Associate Professor of Medicine, University of Minnesota Medical School, Minneapolis 14, Minnesota. 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