What does this research mean for the field?

Sublethal exposure to pesticide mixtures and elevated temperatures interact to significantly alter transcriptomic profiles and long-term metabolic rates in brown trout, despite not affecting immediate survival, growth, or susceptibility to proliferative kidney disease. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The aim is to examine the physiological and transcriptomic effects of multiple environmental stressors on juvenile brown trout.

May 30, 2025The Science of The Total EnvironmentOpen Access

Physiological and transcriptomic responses in brown trout, Salmo trutta, to multiple stressors: Pesticide mixtures, elevated water temperature and the proliferative kidney disease

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Authors

AVAnne-Sophie Voisin KRKristina Rehberger MFMelanie Fasel

Discussion

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Overview

Randomized trial investigates physiological and transcriptomic effects of pesticide mixtures and temperature on juvenile brown trout, highlighting environmental impacts.

Key Points

The aim is to examine the physiological and transcriptomic effects of multiple environmental stressors on juvenile brown trout.
Juvenile brown trout acclimated to 12 or 15 °C were exposed to pesticide mixtures for 14 days and later infected with T. bryosalmonae.
A transcriptomic analysis was conducted using RNA-Seq and RT-qPCR for gene expression evaluation.
Basal oxygen consumption was measured 2.5 months post-exposure to assess metabolic trade-offs.
No mortality or changes in growth, hematocrit, or organ indices occurred due to pesticide exposure.
Differentially expressed genes were significantly greater at 15 °C exposure, with a notable decrease in temperature-induced gene expression in the presence of pesticides.
Basal oxygen consumption decreased after exposure to higher pesticide concentration at 15 °C, indicating potential metabolic trade-offs.

Cite This Study

Voisin et al. (2025) studied this question.

synapsesocial.com/papers/6a21d4b84e02479be07c2fba https://doi.org/10.1016/j.scitotenv.2025.179727

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May 30, 2025The Science of The Total EnvironmentOpen Access

Physiological and transcriptomic responses in brown trout, Salmo trutta, to multiple stressors: Pesticide mixtures, elevated water temperature and the proliferative kidney disease

View Full Paper

Ask AI

Bookmark

Authors

AVAnne-Sophie Voisin KRKristina Rehberger MFMelanie Fasel

Discussion

Member takes

Overview

Randomized trial investigates physiological and transcriptomic effects of pesticide mixtures and temperature on juvenile brown trout, highlighting environmental impacts.

Key Points

The aim is to examine the physiological and transcriptomic effects of multiple environmental stressors on juvenile brown trout.
Juvenile brown trout acclimated to 12 or 15 °C were exposed to pesticide mixtures for 14 days and later infected with T. bryosalmonae.
A transcriptomic analysis was conducted using RNA-Seq and RT-qPCR for gene expression evaluation.
Basal oxygen consumption was measured 2.5 months post-exposure to assess metabolic trade-offs.
No mortality or changes in growth, hematocrit, or organ indices occurred due to pesticide exposure.
Differentially expressed genes were significantly greater at 15 °C exposure, with a notable decrease in temperature-induced gene expression in the presence of pesticides.
Basal oxygen consumption decreased after exposure to higher pesticide concentration at 15 °C, indicating potential metabolic trade-offs.

Cite This Study

Voisin et al. (2025) studied this question.

synapsesocial.com/papers/6a21d4b84e02479be07c2fba https://doi.org/10.1016/j.scitotenv.2025.179727

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