Key result
Gadolinium-enhanced MR imaging provided approximately twice the signal-to-noise ratio compared to T2-weighted images for discriminating fibrous cap from lipid core (36.6 vs 17.5; P<.001).
Why the study?
Does gadolinium-enhanced double-oblique MR imaging improve the signal-to-noise ratio for characterizing carotid atheroma compared to T2-weighted MR images in subjects with carotid atherosclerosis?
Population
9 subjects with carotid atherosclerosis
Comparison
Gadolinium-enhanced double-oblique, double… vs T2-weighted MR images
Design
Case_series
Authors
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May aid carotid plaque characterization on MRI; hypothesis-generating and requires prospective validation before practice change.
Observational (n=9)
Does gadolinium-enhanced double-oblique MR imaging improve the signal-to-noise ratio for characterizing carotid atheroma compared to T2-weighted MR images in subjects with carotid atherosclerosis?
Absolute Event Rate: 36.6% vs 17.5%
p-value: p=<.001
Gadolinium-enhanced MR imaging significantly improves the signal-to-noise ratio for characterizing carotid atheroma morphology compared to T2-weighted imaging.
Wasserman et al. (2002) conducted an observational in Carotid atherosclerosis (n=9). Gadolinium-enhanced double-oblique MR imaging vs. T2-weighted MR images was evaluated on Signal-to-noise ratio for discriminating fibrous cap from lipid core (p=<.001). Gadolinium-enhanced MR imaging provided approximately twice the signal-to-noise ratio compared to T2-weighted images for discriminating fibrous cap from lipid core (36.6 vs 17.5; P<.001).
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