Key result
Erectile dysfunction was associated with significantly prolonged P wave dispersion compared to healthy controls (48.1 ± 5.9 vs. 38.0 ± 3.9, p < 0.05), correlating with disease severity.
Why the study?
PWD is a non-invasive electrocardiographic predictor for atrial fibrillation, but whether it is prolonged in men with erectile dysfunction and related to disease severity remained to be investigated.
Does erectile dysfunction associate with prolonged P wave dispersion in men without known cardiovascular disease?
Case-Control (n=72)
Does erectile dysfunction associate with prolonged P wave dispersion in men without known cardiovascular disease?
Erectile dysfunction is associated with prolonged P wave dispersion, suggesting a potential link between ED and an increased risk of atrial arrhythmias likely mediated by autonomic and endothelial dysfunction.
Background and aims P wave dispersion (PWD) has been reported to be a non-invasive electrocardiographic predictor for atrial fibrillation. The aim of this study is to evaluate PWD between men with erectile dysfunction (ED) and healthy controls in order to investigate whether PWD was prolonged in patients with ED and related to severity of the disease. Methods This study included a total of 72 men (42 patients with ED and 30 healthy controls). Demographic data and clinical features were recorded on admission. An electrocardiographic evaluation was obtained to measure PWD values for both patients and controls. Results Maximum P wave duration was 108.5 ± 4.7 and 108.3 ± 4.3 in ED group and control group, respectively ( p = 0.748). Minumum P wave duration was significantly higher in the control group than in the ED group. PWD was 48.1 ± 5.9 in the ED group. As a result, PWD was prolonged in patients with ED (48.1 ± 5.9 vs. 38.0 ± 3.9, p < 0.05). A significant negative correlation was observed between IIEF score and PWD values ( p < 0.05, r = −0.662). Conclusions Patients with ED exhibited prolonged PWD values compared with normal controls. In addition, PWD was found to be associated with severity of the disease.
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Öncel et al. (2019) conducted a case-control in Erectile dysfunction (n=72). Erectile dysfunction vs. Healthy controls was evaluated on P wave dispersion (PWD) (p=< 0.05). Erectile dysfunction was associated with significantly prolonged P wave dispersion compared to healthy controls (48.1 ± 5.9 vs. 38.0 ± 3.9, p < 0.05), correlating with disease severity.
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