Key result
Diffuse large B-cell lymphoma can mimic cardiac amyloidosis on cardiac magnetic resonance, presenting a diagnostic challenge in patients with transformed Waldenström's macroglobulinemia.
Cardiac lymphoma can mimic cardiac amyloidosis on CMR, requiring heightened suspicion for early diagnosis and treatment.
Raises diagnostic caution for lymphoma in WM with amyloid-like CMR; single case leaves biopsy role open for validation.
Our case highlights that cardiac lymphoma may mimic amyloid infiltration of the myocardium on cardiac magnetic resonance (CMR), and is a particularly challenging diagnosis in the setting of transformed Waldenström's macroglobulinemia. Heightened suspicion and early diagnosis of cardiac lymphoma is paramount as chemotherapy has been demonstrated to portent an increased survival rate.
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Lau et al. (2017) studied this question. Diffuse large B-cell lymphoma can mimic cardiac amyloidosis on cardiac magnetic resonance, presenting a diagnostic challenge in patients with transformed Waldenström's macroglobulinemia.
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