Primary cardiac lymphoma can present without intracardiac masses mimicking infiltrative cardiomyopathy, and LV systolic function can fully recover following appropriate chemotherapy.
Suggests full systolic recovery is possible with chemotherapy in primary cardiac lymphoma mimicking cardiomyopathy; single case leaves open broader applicability.
Primary cardiac lymphoma is a rare malignancy which has been described as thickened myocardium due to the infiltration of atypical lymphocytes and accompanying intracardiac masses. Here, we report a case of a primary cardiac lymphoma without demonstrable intracardiac masses, mimicking infiltrative cardiomyopathy. A 40-year-old male presented with exertional dyspnoea and was diagnosed as having restrictive cardiomyopathy with severely decreased LV systolic function. Endomyocardial biopsy was performed and the diagnosis of primary cardiac lymphoma was confirmed. After appropriate chemotherapy, he recovered his systolic function fully.
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Lee et al. (2012) studied this question.
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