January 1, 1975Proceedings of the National Academy of Sciences111 citationsOpen Access

Neutron Diffraction Studies on the Location of Water in Lecithin Bilayer Model Membranes

GZGiuseppe Zaccaı̈Institut Laue-Langevin JBJ. Kent BlasieUniversity of Pennsylvania BSB. P. SchoenbornLos Alamos National Laboratory

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Abstract

Lamellar neutron diffraction from oriented multilayers of hydrated dipalmitoyl lecithin was phased by isomorphous H(2)O-D(2)O exchange and swelling techniques. Bound water sites were located in the polar head group region of the bilayer profile. A 6-A resolution structure based on the neutron scattering density profile is proposed for the bilayer. It is consistent with the electron density profile from x-ray diffraction.

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synapsesocial.com/papers/6a21fe3b5c15637a5057f64a https://doi.org/https://doi.org/10.1073/pnas.72.1.376

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