Key result
Hypertrophic non-obstructive cardiomyopathy was characterized by the largest ventricular gradient oriented to the right, with Gx values (-92.2 +/- 32.0 micro V . sec) significantly more negative than other groups.
Why the study?
What is the clinical significance of a right-oriented ventricular gradient (negative Gx) across different cardiac conditions?
Observational (n=1,000)
What is the clinical significance of a right-oriented ventricular gradient (negative Gx) across different cardiac conditions?
A right-oriented ventricular gradient (negative Gx) on vectorcardiography is highly characteristic of hypertrophic non-obstructive cardiomyopathy compared to other cardiac conditions.
In 1,000 patients on whom vectorcardiography was performed, ventricular gradients (G) were calculated using a micro-computer. In 73 patients, excluding those with dextrocardia and atrial fibrillation, the X component of the ventricular gradient (Gx) showed a negative value. These patients with a negative Gx were divided into the following 10 subgroups and their G were compared: hypertrophic non-obstructive cardiomyopathy (HCM), hypertrophic obstructive cardiomyopathy (HOCM), congestive cardiomyopathy, concentric left ventricular hypertrophy, aortic valvular disease, ischemic heart disease, myocardial infarction, pericarditis, right ventricular hypertrophy and others. The HCM group was the most characteristic with large Aqrs oriented to the left, the largest At oriented to the right and the largest G oriented to the right. Gx in this group showed values more negative than -50 micro V . sec (-92.2 +/- 32.0) and significantly differed from other groups.
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Motomura et al. (1982) conducted an observational in Ventricular gradient with a right orientation (n=1,000). Hypertrophic non-obstructive cardiomyopathy (HCM) vs. Other cardiac disease subgroups was evaluated on X component of the ventricular gradient (Gx). Hypertrophic non-obstructive cardiomyopathy was characterized by the largest ventricular gradient oriented to the right, with Gx values (-92.2 +/- 32.0 micro V . sec) significantly more negative than other groups.
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