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This review discusses the implications of abnormal wall stress and the law of Laplace equation at various stages in the pathophysiology of hypertensive heart disease.
This review discusses the implications of abnormal wall stress and the law of Laplace in the pathophysiology of hypertensive heart disease.
May inform mechanistic models of hypertensive heart disease; leaves open prospective outcome studies on wall stress modulation.
The precise role that abnormal wall stress may play in the pathophysiology of hypertensive heart disease is not known. Hypertension is almost unique in that it ultimately affects all parts of the law of Laplace equation, i.e. intraventricular pressure changes and with the advent of left ventricular hypertrophy both internal radius and wall thickness alter. If heart failure supervenes the components of the equation change once more. This article will discuss the implications of abnormal wall stress at these various stages in hypertensive heart disease.
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James et al. (2000) conducted a review in Hypertensive heart disease. Abnormal wall stress was evaluated. This review discusses the implications of abnormal wall stress and the law of Laplace equation at various stages in the pathophysiology of hypertensive heart disease.
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