October 31, 2022National Journal of Community MedicineOpen Access

Reduced Heart Rate Variability as A Risk Factor for Cardiovascular Disease in Young Healthy Adults with Low and High Body Mass Indexes – A Descriptive Study

Q: What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Healthy (n=160). Intervention: Abnormal Body Mass Index (Underweight, Overweight, Obese) vs. Normal weight. Primary outcome: Heart rate variability indices (e.g., HF log power n.u.) (p=<0.001).

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Key result

Heart rate variability indices were significantly reduced in underweight, overweight, and obese young adults compared to normal-weight individuals, demonstrating an inverted U-shaped relationship with BMI.

Why the study?

Heart rate variability assesses autonomic nervous system input to the heart, but studies on its impact in underweight individuals are limited.

Does abnormal BMI (underweight, overweight, or obese) reduce heart rate variability in healthy young adults?

Population

Healthy young adult volunteers between 18 and 25 years of age

Comparison

Different BMI categories compared to normal weight

Design

Cross-sectional study

Authors

SNS NiveathaPondicherry Institute of Medical Sciences ARAruna RajuAll India Institute of Medical Sciences RLR LathaNational Institute of Technology Tiruchirappalli

Discussion

Member takes

Implication

Abnormal BMI may associate with reduced HRV in young adults; leaves open causality and need for longitudinal studies.

Study Design

Type

Cross-Sectional (n=160)

Multicenter

Structured PICO

Does abnormal BMI (underweight, overweight, or obese) reduce heart rate variability in healthy young adults?

Population

160 healthy young adults aged 18 to 25 years were evaluated to assess the relationship between body mass index, waist circumference, and heart rate variability.

Exposure

Abnormal BMI categories: Underweight (<18.5 kg/m2), overweight (25-29.9 kg/m2), and obese (≥30 kg/m2)

Comparator

Normal weight BMI category (18.5-24.9 kg/m2)

Outcome

Heart rate variability (HRV) indices (SDNN, RMSSD, HF, LF, LF/HF ratio) measured via 5-minute ECG recordingsurrogate

Main Result

p-value: p=<0.001

Both underweight and overweight/obese BMI categories are associated with reduced heart rate variability in young adults, suggesting an inverted U-shaped relationship between BMI and cardiac autonomic function.

Limitations

Physical activity of the subjects was not considered, which can influence cardiac autonomic behavior.
Did not consider the physical activity of the subjects, which can influence cardiac autonomic behavior

Cite This Study

Niveatha et al. (2022) conducted a cross-sectional in Healthy (n=160). Abnormal Body Mass Index (Underweight, Overweight, Obese) vs. Normal weight was evaluated on Heart rate variability indices (e.g., HF log power n.u.) (p=<0.001). Heart rate variability indices were significantly reduced in underweight, overweight, and obese young adults compared to normal-weight individuals, demonstrating an inverted U-shaped relationship with BMI.

synapsesocial.com/papers/6a220e6e89ae9bae15e22a0b https://doi.org/10.55489/njcm.131020222414

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Reduced Heart Rate Variability as A Risk Factor for Cardiovascular Disease in Young Healthy Adults with Low and High Body Mass Indexes – A Descriptive Study

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Reduced Heart Rate Variability as A Risk Factor for Cardiovascular Disease in Young Healthy Adults with Low and High Body Mass Indexes – A Descriptive Study

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Also Consider

Also Consider