Key result
Obesity in young adults was associated with a statistically significant reduction in parasympathetic activity, evidenced by lower SDNN (48.29 vs 59.87 ms, p=0.001), and increased sympathetic activity.
Why the study?
Obesity is associated with autonomic dysfunction predisposing young people to increased cardiovascular morbidity and mortality, prompting investigation into how obesity affects cardiac autonomic activity.
Does obesity affect cardiac autonomic activity (heart rate variability) in young adults?
Cross-Sectional (n=60)
No
Does obesity affect cardiac autonomic activity (heart rate variability) in young adults?
Absolute Event Rate: 48.2887% vs 59.873%
p-value: p=0.001
Obesity in young adults is associated with cardiac autonomic dysfunction, characterized by reduced parasympathetic and increased sympathetic activity.
Obesity may impair cardiac autonomic function in young adults; leaves open whether HRV changes predict outcomes or warrant intervention.
Introduction: Heart Rate Variability is a common non – invasive technique with significant diagnostic, clinical and research application. Obesity is seen to be associated with autonomic dysfunction with increased sympathetic activity and decreased parasympathetic activity in young people predisposing them to increased cardiovascular mortality and morbidity. The aim of our study was to see how obesity effects cardiac autonomic activity in normal weight and obese individuals. Materials and Methods: The study was conducted on 60 young individuals between 18-25 years divided into two groups of 30 each based on their BMI: Group I – Normal weight group with BMI – 18-22.9 Kg/ m2 and Group II – Obese subjects with BMI ? 25 Kg/m2. HRV was done in both the groups and was analyzed for time domain and frequency domain parameters. The data was analyzed by using students ‘t test’ and Chi-square test. Correlation was done between various anthropometric measures and HRV using Pearson’s correlation coefficient. Results: With the exception of height and neck circumference, all the anthropometric parameters were significantly higher in Group II compared to Group I While analyzing HRV for frequency domain parameters, LF (nu) and LF/HF were significantly lower in Group I compare to Group II. Time domain parameters of SDNN, RMSSD and pNN50 were significantly higher in Group 1. Conclusion: Our study showed a statistically significant reduction in parasympathetic activity and an increase in sympathetic activity in the obese compared to controls.
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Sinha et al. (2019) conducted a cross-sectional in Obesity (n=60). Obesity (BMI ≥ 25 Kg/m2) vs. Normal weight (BMI 18-22.9 Kg/m2) was evaluated on SDNN (ms) (p=0.001). Obesity in young adults was associated with a statistically significant reduction in parasympathetic activity, evidenced by lower SDNN (48.29 vs 59.87 ms, p=0.001), and increased sympathetic activity.
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