Key result
Cognitive-behavioural therapy for lifestyle modification significantly reduced weight (MD -2.633; 95% CI -4.322 to -0.943; p<0.003) and other cardiovascular risk factors at 18 months.
Why the study?
The efficacy of cognitive-behavioural therapy for lifestyle modification in patients with metabolic syndrome required testing.
Does cognitive-behavioural therapy improve metabolic syndrome parameters and cardiovascular risk factors in patients with metabolic syndrome?
RCT (n=76)
Does cognitive-behavioural therapy improve metabolic syndrome parameters and cardiovascular risk factors in patients with metabolic syndrome?
Mean Difference: -2.633 (95% CI -4.322–-0.943)
p-value: p=<.003
A 12-week group cognitive-behavioural therapy program significantly improves anthropometric measures, blood pressure, and cardiovascular risk scores in patients with metabolic syndrome at 18 months.
CBT supports integration into metabolic syndrome care; extends RCT evidence for sustained cardiovascular risk reduction at 18 months.
OBJECTIVE: To test the efficacy of cognitive-behavioural therapy (CBT) for lifestyle modification in patients with metabolic syndrome (MetS). DESIGN: 76 MetS patients completed this clinical trial, with 18 months follow-up. 45 participants from the experimental group (EG - CBT) and 31 to the control group (CG - usual care). The CBT programme was performed by a psychologist in a face-to-face group format, during 12 weekly sessions lasting 90 minutes. The intervention for the CG consisted of workshops with basic information about MetS and it's associated cardiovascular risk. MAIN OUTCOME MEASURES: Efficacy of (CBT) in (MetS) patients. RESULTS: Results showed reduction in weight (mean difference - MD -2.633, 95%CI [-4.322, -0.943]; p<.003), waist circumference (MD -2.944, 95%CI [-5.090, -0.798]; p<.008), body mass index (MD -0.915, 95%CI [-1.494, -0.335]; p<.003), systolic (MD -0.046, 95%CI [-0.685, -0.023]; p<.0002) diastolic blood pressure (MD -4.777, 95%CI [-7.750, -1.804]; p<.002), and cardiovascular risk score after 18 months. An increase in adherence to the Mediterranean diet and assertiveness and a reduction in anger were observed in EG. The CG did not show any significant differences. CONCLUSION: The CBT focused on changes in lifestyle seems to be effective in the reduction of MetS and cardiovascular risk factors. TRIAL REGISTRATION: Registered at clinicaltrials.gov (NCT02949622) - PROMETS (Multimodal Intervention Program for Patients with Metabolic Syndrome).
No takes yet. Share an insight, caveat, or question.
Silva et al. (2022) conducted an RCT in Metabolic syndrome (n=76). Cognitive-behavioural therapy (CBT) vs. Usual care was evaluated on Weight reduction (MD -2.633, 95% CI -4.322, -0.943, p=<.003). Cognitive-behavioural therapy for lifestyle modification significantly reduced weight (MD -2.633; 95% CI -4.322 to -0.943; p<0.003) and other cardiovascular risk factors at 18 months.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: