Why the study?
Are nonobese male patients with familial combined hyperlipidemia more insulin resistant compared with their nonaffected relatives?
Population
Male nonobese, normotensive patients with Familial Combined Hyperlipidemia and their nonaffected relatives…
Design
Case-control
Authors
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Nonobese FCH patients exhibit insulin resistance versus relatives; case-control data leaves open mechanisms and therapeutic implications.
Are nonobese male patients with familial combined hyperlipidemia more insulin resistant compared with their nonaffected relatives?
Nonobese patients with familial combined hyperlipidemia exhibit significant insulin resistance compared to unaffected relatives, which may be partly explained by decreased insulin-induced vasodilation in skeletal muscle.
Bredie et al. (1997) studied this question.
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