Key result
Every 1-unit increase in the visceral adiposity index was associated with a 14% increased likelihood of clinical depression (OR 1.14) among US adults.
Why the study?
Depression is a serious disorder accompanied by emotional and physiological changes, and the association between visceral fat deposition measured by VAI and depression required exploration in the American population.
Does higher Visceral Adiposity Index increase the likelihood of developing depression in adults in the United States?
Cross-Sectional (n=2,577)
Does higher Visceral Adiposity Index increase the likelihood of developing depression in adults in the United States?
Odds Ratio: 1.14 (95% CI 1.04–1.25)
p-value: p=0.004
Higher visceral adiposity index is significantly associated with an increased likelihood of depression among US adults.
Should not yet alter depression screening; leaves open causality and need for prospective studies.
Background: Depression is a serious mental disorder often accompanied by emotional and physiological disorders. Visceral fat index (VAI) is the current standard method in the evaluation of visceral fat deposition. In this study, we explored the association between VAI and depression in the American population using NHANES data. Methods: A total of 2,577 patients were enrolled for this study. Data were collected through structured questionnaires. Subgroup analysis for the relationship between VAI and depression was evaluated using multivariate regression analysis after adjustment for potential confounding factors. Results: For every 1 unit increase in VAI, the clinical depression increased by 14% (OR = 1.14, 95% CI: 1.04-1.25). High VAI scores (T3) increased the highest risk of developing depression (OR = 2.32, 95% CI: 1.2-4.47). Subgroup analysis demonstrated a strong and stable association between VAI and the development of depression. Conclusion: Our study showed that depressive symptoms are associated with a high ratio of visceral adiposity index after controlling confounding factors.
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Lei et al. (2022) conducted a cross-sectional in Depression (n=2,577). Visceral Adiposity Index vs. Lower Visceral Adiposity Index was evaluated on Clinical depression (PHQ-9 score ≥ 10) (OR 1.14, 95% CI 1.04–1.25, p=0.004). Every 1-unit increase in the visceral adiposity index was associated with a 14% increased likelihood of clinical depression (OR 1.14) among US adults.
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