Key result
Left atrial appendage strain and strain rate imaging showed a strong positive correlation with LAA late empty velocity (r=0.886 and r=0.897, respectively; P<0.001).
Why the study?
Does strain and strain rate imaging accurately evaluate left atrial appendage function compared to LAA late empty velocity?
Cross-Sectional (n=57)
Does strain and strain rate imaging accurately evaluate left atrial appendage function compared to LAA late empty velocity?
Effect estimate: r = 0.886 (S) and r = 0.897 (Sr)
p-value: p=<0.001
Strain and strain rate imaging by transesophageal echocardiography strongly correlates with LAA late empty velocity and can identify reduced LAA function in patients with spontaneous echo contrast or thrombus.
Strain imaging may aid LAA function assessment on TEE; leaves open prospective outcome validation before clinical use.
BACKGROUND: This study was planned to assess whether strain rate (Sr) and strain (S) echocardiography is a useful method for functional assessment of the left atrial appendage (LAA). MATERIAL AND METHODS: Fifty-seven consecutive patients underwent a clinically indicated study. LAA late empty velocity (LAAEV) was calculated as a gold standard for left atrial appendage function. Real-time 2-dimensional color Doppler myocardial imaging data were recorded from the LAA at a high frame rate. Analysis was performed for LAA longitudinal strain rate and strain from midsegment of lateral wall of LAA. LAA strain determines regional lengthening expressed as a positive value or shortening expressed as a negative value. Peak systolic values were calculated from the extracted curve. RESULTS: Spearman correlation test results showed a statistically significant positive correlation was between the S, Sr variables and LAAEV (LAAEV vs S; r = 0.886, P < 0.001; LAAEV vs Sr: r = 0.897, P < 0.001, respectively). Strain and strain rate values were also significantly lower in patients with spontaneous echocardiographic contrast when compared with those without (strain; 2.42 +/- 0.98 vs 13.1 +/- 5.9, P < 0.001 and strain rate: 0.97 +/- 0.54 vs 3.34 +/- 1.15, P < 0.001, respectively). In addition, LAA strain and strain rate values were significantly lower in the patients with LAA thrombus (strain; 2.15 +/- 0.96 vs 8.35 +/- 6.9, P < 0.001, strain rate; 0.79 +/- 0.46 vs 2.30 +/- 1.48, P < 0.001, respectively). CONCLUSION: S and Sr imaging can be considered a robust technique for the assessment of the LAA systolic deformation.
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Sevimli et al. (2007) conducted a cross-sectional in Patients undergoing clinically indicated transesophageal echocardiography (n=57). Strain and strain rate imaging vs. LAA late empty velocity (LAAEV) was evaluated on Correlation between strain (S) / strain rate (Sr) and LAA late empty velocity (LAAEV) (r = 0.886 (S) and r = 0.897 (Sr), p=<0.001). Left atrial appendage strain and strain rate imaging showed a strong positive correlation with LAA late empty velocity (r=0.886 and r=0.897, respectively; P<0.001).
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