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The aim is to develop a noninvasive method for visualizing breast vasculature without ionizing radiation or contrast agents.

November 1, 2010Medical PhysicsOpen Access

Photoacoustic angiography of the breast

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The aim is to develop a noninvasive method for visualizing breast vasculature without ionizing radiation or contrast agents.
Used pulsed laser at 800 nm to stimulate photoacoustic waves in the breast.
Detected waves with piezoelectric transducers to create three-dimensional images.
Achieved imaging with 24 s acquisition time and submillimeter spatial resolution.
Obtained clear three-dimensional vascular images with submillimeter resolution to a depth of 40 mm.
Spatial resolution approached 250 micrometers in a 64 x 64 x 50 mm field of view.
Promising potential for dynamic contrast-enhanced imaging without exogenous agents.

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Noninvasive technique visualizes breast vasculature in three dimensions, suggesting future applications in dynamic imaging.

Kruger et al. (2010) studied this question.

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