Key result
Essential hypertension is characterized by increased vascular resistance that progresses over time to a low cardiac output and high resistance pattern with reduced left ventricular compliance.
This review highlights the progressive hemodynamic changes in essential hypertension, emphasizing the transition from high cardiac output to high vascular resistance and structural cardiac changes over time.
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May inform serial hemodynamic monitoring in essential hypertension; leaves open whether early intervention alters progression to low-output, stiff LV.
Per Lund‐Johansen (1987) conducted a review in Essential hypertension. Essential hypertension vs. Normotensive age-matched controls was evaluated. Essential hypertension is characterized by increased vascular resistance that progresses over time to a low cardiac output and high resistance pattern with reduced left ventricular compliance.
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