Key result
Food ingestion decreased systolic blood pressure in diabetic patients by a maximum of 25+/-5 mmHg due to a lack of compensatory sympathetic activation, but did not affect healthy controls.
Why the study?
Does food ingestion induce postprandial hypotension due to autonomic dysfunction in patients with diabetes mellitus compared to healthy volunteers?
Population
10 patients with diabetes mellitus and 10 healthy volunteers
Comparison
Standardized meal ingestion and postural changes vs Healthy volunteers (controls)
Design
Case-control
Authors
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Postprandial BP monitoring may merit consideration in diabetes; leaves open sympathetic autonomic impairment as causal mechanism.
Case-Control (n=20)
Does food ingestion induce postprandial hypotension due to autonomic dysfunction in patients with diabetes mellitus compared to healthy volunteers?
Postprandial hypotension in diabetic patients is associated with a lack of compensatory sympathetic activation rather than changes in parasympathetic tone.
Tanakaya et al. (2007) conducted a case-control in Diabetes mellitus (n=20). Diabetes mellitus vs. Healthy volunteers was evaluated on Systolic blood pressure reduction after food ingestion. Food ingestion decreased systolic blood pressure in diabetic patients by a maximum of 25+/-5 mmHg due to a lack of compensatory sympathetic activation, but did not affect healthy controls.
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