Key result
Assisted reproductive technology links to lower resting HRV in children, potentially preceding premature hypertension.
Observational
Suggests monitoring for early hypertension risk in ART children; leaves open whether reduced HRV is causal or confounded.
We observed that children conceived by assisted reproductive technology (both frozen and fresh embryo transfer) had lowered heart rate variability during rest as compared with children conceived naturally. During physiological stress maneuvers, however, the cardiovascular autonomic nervous regulation was comparable between children conceived by assisted reproductive technologies and naturally. Our findings highlight the potential that lowered heart rate variability during rest in children conceived by assisted reproductive technologies may precede premature hypertension.
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Mizrak et al. (2023) conducted an observational in Children conceived by assisted reproductive technology. Assisted reproductive technology (frozen or fresh embryo transfer) vs. Natural conception was evaluated on Heart rate variability during rest. Children conceived by assisted reproductive technology had lowered heart rate variability during rest compared with naturally conceived children, which may precede premature hypertension.
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