What is the clinical evidence from this study?

Population: Ventricular tachycardia (n=5). Intervention: CARDIO-RT software vs. Manual target transfer. Primary outcome: Quality of substrate transfer.

What question did this study set out to answer?

The aim is to evaluate a new quality assurance process for merging electroanatomical mapping and radiotherapy imaging for better cardiac procedures.

December 26, 2022Physics and Imaging in Radiation OncologyOpen Access

Quality assurance process within the RAdiosurgery for VENtricular TAchycardia (RAVENTA) trial for the fusion of electroanatomical mapping and radiotherapy planning imaging data in cardiac radioablation

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Key result

Target transport using CARDIO-RT software showed substantial structural differences compared to manual target transfer in 5 clinical cases.

Why the study?

To assess a novel quality assurance process for electroanatomical mapping to radiotherapy planning imaging target transport within the multicenter RAVENTA trial.

Does target transport using CARDIO-RT software differ from manual target transfer for the fusion of electroanatomical mapping and radiotherapy planning imaging in cardiac radioablation?

Key Points

The aim is to evaluate a new quality assurance process for merging electroanatomical mapping and radiotherapy imaging for better cardiac procedures.
Multi-center trial framework assessed novel software CARDIO-RT for EAM to RTPI registration.
Target transport evaluated across five clinical cases using structural analyses.
Manual and semi-automated methods were compared for accuracy.
Substantial differences were observed in target transfer accuracy between manual methods and CARDIO-RT, indicating that CARDIO-RT provides enhanced precision.
Results from five cases demonstrated improved substrate transfer with the use of CARDIO-RT.

Structured PICO

Does target transport using CARDIO-RT software differ from manual target transfer for the fusion of electroanatomical mapping and radiotherapy planning imaging in cardiac radioablation?

Population

5 clinical cases evaluated for the quality of substrate transfer in cardiac radioablation for ventricular tachycardia.

Intervention

Target transport using CARDIO-RT software for platform-independent registration of electroanatomical mapping (EAM) and radiotherapy planning imaging (RTPI)

Comparator

Manual target transfer

Outcome

Quality of substrate transfer and structural differencessurrogate

A novel software (CARDIO-RT) for fusing electroanatomical mapping and radiotherapy planning imaging shows substantial differences compared to manual target transfer, highlighting the importance of standardized quality assurance in cardiac radioablation.

Implication

Differences urge standardized QA in cardiac radioablation; leaves open software accuracy versus manual methods pending prospective validation.

Abstract

A novel quality assurance process for electroanatomical mapping (EAM)-to-radiotherapy planning imaging (RTPI) target transport was assessed within the multi-center multi-platform framework of the RAdiosurgery for VENtricular TAchycardia (RAVENTA) trial. A stand-alone software (CARDIO-RT) was developed to enable platform independent registration of EAM and RTPI of the left ventricle (LV), based on pre-generated radiotherapy contours (RTC). LV-RTC were automatically segmented into the American-Heart-Association 17-segment-model and a manual 3D-3D method based on EAM 3D-geometry data and a semi-automated 2D-3D method based on EAM screenshot projections were developed. The quality of substrate transfer was evaluated in five clinical cases and the structural analyses showed substantial differences between manual target transfer and target transport using CARDIO-RT.

Discussion

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Published by Physics and Imaging in Radiation Oncology · CC BY-NC-ND

Cite This Study

Mayinger et al. (2022) studied Ventricular tachycardia (n=5). CARDIO-RT software vs. Manual target transfer was evaluated on Quality of substrate transfer. Target transport using CARDIO-RT software showed substantial structural differences compared to manual target transfer in 5 clinical cases.

synapsesocial.com/papers/6a2229fee8ef4064f24ec86c https://doi.org/10.1016/j.phro.2022.12.003

Topics

Ventricular arrhythmias

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Implication

Differences urge standardized QA in cardiac radioablation; leaves open software accuracy versus manual methods pending prospective validation.

Quality assurance process within the RAdiosurgery for VENtricular TAchycardia (RAVENTA) trial for the fusion of electroanatomical mapping and radiotherapy planning imaging data in cardiac radioablation

Key Points

Structured PICO

Implication

Abstract

Discussion

Figures from the paper

Cite This Study

Topics

Quality assurance process within the RAdiosurgery for VENtricular TAchycardia (RAVENTA) trial for the fusion of electroanatomical mapping and radiotherapy planning imaging data in cardiac radioablation

Key Points

Structured PICO

Implication

Abstract

Discussion

Figures from the paper

Cite This Study

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