Key result
Cardiac resynchronization via biventricular or left univentricular pacing resulted in dramatic improvement of left ventricular dimension, function, and clinical state in 3 pacemaker-dependent children.
Why the study?
Does cardiac resynchronization therapy improve left ventricular dimension, function, and clinical state in children with heart failure dependent on chronic right ventricular apical pacing?
Case Report (n=3)
Does cardiac resynchronization therapy improve left ventricular dimension, function, and clinical state in children with heart failure dependent on chronic right ventricular apical pacing?
Cardiac resynchronization therapy (biventricular or left univentricular pacing) may improve LV function and clinical state in pacemaker-dependent children with heart failure induced by chronic RV apical pacing.
Answers are grounded in this paper and cite their sources.
May support CRT consideration in select children with pacing-induced HF; hypothesis-generating case series requiring prospective validation.
Three patients with heart failure after chronic right ventricular apical pacing were treated with resynchronization. Biventricular pacing was used for two patients, and the other was treated with left univentricular pacing. In all patients, we observed a dramatic improvement of left ventricular dimension, function, and clinical state. We conclude that biventricular or left ventricular pacing is superior to right ventricular apical pacing in children who are pacemaker-dependent.
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Beek et al. (2006) conducted a case report in Heart failure after chronic right ventricular apical pacing (n=3). Cardiac resynchronization (biventricular or left univentricular pacing) vs. Right ventricular apical pacing (prior state) was evaluated on Left ventricular dimension, function, and clinical state. Cardiac resynchronization via biventricular or left univentricular pacing resulted in dramatic improvement of left ventricular dimension, function, and clinical state in 3 pacemaker-dependent children.
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