Key result
Continuing to smoke compared to quitting was associated with higher 5-year mortality (22% vs 15%; RR 1.55, 95% CI 1.29-1.85) in patients with coronary artery disease.
Why the study?
Does smoking cessation reduce mortality in smokers with angiographically proved coronary artery disease?
Cohort (n=4,165)
Yes
Does smoking cessation reduce mortality in smokers with angiographically proved coronary artery disease?
Relative Risk: 1.55 (95% CI 1.29–1.85)
Absolute Event Rate: 22% vs 15%
Smoking cessation significantly reduces 5-year mortality, including MI-associated and sudden death, in patients with established coronary artery disease.
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Supports smoking cessation in CAD patients; extends observational data but leaves causality open for RCTs.
Ronald E. Vlietstra (1986) conducted a cohort in Coronary artery disease (n=4,165). Continued smoking vs. Quit smoking was evaluated on Mortality (RR 1.55, 95% CI 1.29-1.85). Continuing to smoke compared to quitting was associated with higher 5-year mortality (22% vs 15%; RR 1.55, 95% CI 1.29-1.85) in patients with coronary artery disease.
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