Why the study?
Although smoking is a major preventable risk factor, the 'smoker's paradox' suggests better survival after acute myocardial infarction, prompting investigation into smoking's impact in stable coronary artery disease.
Does smoking increase the risk of mortality and cardiovascular outcomes in patients with stable coronary artery disease?
Population
32,378 patients with stable coronary artery disease
Comparison
Current smokers vs former smokers vs never-smokers
Design
International observational registry analysis
Follow-up
Five years
Authors
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Highlights elevated mortality with smoking in stable CAD; challenges smoker's paradox yet leaves causality open.
Does smoking increase the risk of mortality and cardiovascular outcomes in patients with stable coronary artery disease?
In patients with stable coronary artery disease, current and former smoking are associated with a significantly increased risk of mortality and cardiovascular events compared to never smoking, refuting the 'smoker's paradox'.
Bouabdallaoui et al. (2020) studied this question.
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